MRI has become the preferred choice for medical diagnosis due to its
non-invasive and non-radioactive nature. Compared with other imaging
modalities such as CT and Ultrasound, MRI not only provides super
physical and structural feature, but also functional chemical
information of the human body. However, MRI is still too expensive
for widespread clinical applications in developing countries including
China and India. With rising trend in cancer and other deadly
diseases, there is a dire need for high quality MRI imaging at
affordable cost.” says Prof Q.Y. Ma, leading Scientist in the MRI
field and Co-Founder of Time Medical Inc. (TiMed).
For magnetic resonance imaging (MRI), the higher the magnet field, the
better the image quality. High-field MRI system market is dominated
by multinational companies and these manufacturers have been trying to
improve imaging resolution by increasing the magnetic field strength.
The field strength for major clinical MRI systems has progressed from
0.3 Telsa (T) to 1.5T and continued to 3T (the highest field strength
allowed for human imaging), with system price around US$0.5M, US$1.5M
and US$3M respectively.
One of the key components in a MRI system is the radio frequency (RF)
coil which detects the MR signal from the object during the imaging
and could be referred as “the lens of a camera”. Currently the
market is facing a challenge in that MRI systems fitted with copper RF
coils have already reached a limit in resolution and this barrier
cannot be overcome by increasing magnetic field strength due to health
and safety concerns.
Furthermore, while MRI is recognised as the most sensitive and safer
medical imaging tool, it is more expensive compared to CT and
ultrasound imaging tools. Statistic shows that China and India have 1
MRI system per 1 million population as compared to 35 MRI systems
per 1 million population in US and Japan; there is an
estimated 2000 MRI systems in China, four times lower than CT
machines, and the reason is believed to be the high cost of MRI
system, limiting its applications in healthcare.

Today, a group of Scientists from Columbia University, Harvard Medical
School and University of Hong Kong successfully created the world-most
sensitive coil for MRI system - High Temperature Superconductor (HTS)
coil. This breakthrough technology could greatly improve the imaging
quality of medical diagnosis by a significant 300%-500%. It means
that the resolution of a low-field 0.3T MRI system is increased to
that of a 1.5T system without increasing the magnetic field. This also
means that an advanced 3T MRI system could have the equivalent
resolution of over 6T, allowing radiologists to see features not
observable with the best of today’s MRI systems. More importantly,
TiMed’s technologies also drastically reduce the medical imaging cost
by as much as 50%, making MRI affordable to more people.
At the RSNA 2007, Dr. Elias Zerhouni, President of National Institute
of Health (NIH) Center claimed “Imaging in vivo is the future of
medicine!” in his keynote speech. This means one could image human
cell at microscopic molecularly level without actually touching the
cell! MRI is the most used method for in vivo microscopic imaging and
TiMed’s technology could provide the best tool for “Imaging In vivo!”
TiMed team demonstrated the ability to achieve a micro image with the
highest resolution of 25um at only 2T using the HTS coil tech (see
figure one). The team also demonstrated 10-fold improvement in
sensitivity for Na (Sodium) imaging which open the door for direct
measure of tumor issue.
TiMed’s innovation will have major impact in medical science and
technology. The world can now use low-field MRI to get what used to
be high-field results and at a significantly lower cost. TiMed’s
technologies produce the world best RF coil that empowers radiologists
to provide faster, more definitive and affordable diagnosis to benefit
patients all over the world.

About Time Medical Inc.

TiMed was founded by a group of Scientists trained at Columbia
University, Harvard Medical School and the University of Hong Kong.
Led by founder Prof. Q.Y. Ma, the R&D team pioneered the use of High-
Temperature Superconducting materials in MRI and is the first in the
world to develop superconducting RF coil that overcomes the resolution
limit of conventional copper coils, and make possible a significant
improvement in resolution by 300%-500% without a commensurate increase
in magnetic field strength.
The team has generated five patents, published more than 50 papers in
the MRI field and owns core IPs licensed from Columbia University.
TiMed holds close relationship with world leading medical research
centers such as University of California at San Francisco, Harvard
BWH, Merck and some local medical centers in China for its HTS coils

As a world leading fully-integrated MRI company, TiMed generates
revenue by selling HTS coils and components to MRI manufacturers to
retrofit into existing MRI systems as well as through launching its
own state-of-the-art MRI systems. TiMed will continue the pursuit in
global scientific, technological and clinical excellence to develop
the world’s most sensitive and accurate imaging systems for detecting
and fighting major illnesses. .